Publications Equipe Hétérocycles et Peptides



« Synthesis and characterization of water-soluble macrocyclic peptides stabilizing protein α-turn. » Wang, L.; Coric P.; Zhu, K.; Liu, W.-Q.; Vidal, M.; Bouaziz, S.; Broussy, S. Org. Biomol. Chem. 201816, 459-471.

“Colorimetric immunoassays for the screening and specificity evaluation of molecules disturbing VEGFs/VEGFRs interactions.” Trapiella-Alfonso L.; Broussy S.; Liu W.-Q.; Vidal M.; Lecarpentier E.; Tsatsaris V.; Gagey-Eilstein N. Biochem. 2018, 544, 114-120.


« Light on Unsaturated Hydrocarbons – “Gotta Heterofunctionalize Them All” » Menigaux, D.; Belmont, P.; Brachet, E. Eur. J. Org. Chem. 2017, 15, 2008-2055.

« Identification of peptidic antagonists of vascular endothelial growth factor receptor-1 by scanning the binding epitopes of its ligands. » Wang, L.; Zhou, L.; Reille-Seroussi, M.; Gagey-Eilstein, N.; Broussy, S.; Ji, L.; Vidal, M.; Liu, W.-Q. J. Med. Chem201760, 6598-6606.

« VEGFR1 domain 2 covalent labeling with horseradish peroxidase: development of a displacement assay on VEGF. » Reille-Seroussi, M.; Gaucher, J.-F.; Cussac, L.-A., Broutin, I.; Vidal, M.; Broussy, S. Anal. Biochem.2017530, 107-112.


« Phosphine-Triggered Selectivity Switch in Silver-Catalyzed o-Alkynylbenzohydroxamic Acid Cycloisomerizations » Bantreil, X. ; Bourderioux, A. ; Mateo,P. ; Hagerman, C. E.; Selkti, M.; Brachet, E.; and Belmont P. Org. Lett. 2016, 18, 4814-4817.

« Visible light amination/Smiles cascade: access to phthalazine derivatives » Brachet, E.;Marzo, L.; Selkti, M.; König, B.; Belmont, P.  Chem. Sci. 2016, 7, 5002-5006.

« Inverse Electron Demand Diels‐Alder (IEDDA) Reactions: Synthesis of Heterocycles and Natural Products along with bioorthogonal and material sciences applications » Brachet, E.; Belmont, P. Curr. Org. Chem. 2016, 20, 2136-2160.

« Biophysical Studies of the Induced Dimerization of Human VEGF Receptor 1 Binding Domain by Divalent Metals Competing with VEGF-A. » Gaucher, J-F.; Reille-Seroussi, M.; Gagey-Eilstein, N.; Broussy, S.; Coric, P.; Seijo, B.; et al. PLoS ONE201611(12): e0167755.

« Guttiferone A Aggregates Modulate Silent Information Regulator 1 (SIRT1) Activity. » Cottet, K.; Xu, B.; Coric, P.; Bouaziz, S.; Michel, S.; Vidal, M.; Lallemand, M.-C.; Broussy, S. J. Med. Chem201659, 9560-9566.


« Inhibition of VEGF/VEGFR interaction by a series of C-terminal modified cyclic peptides.” Wang L.; Broussy S.; Gagey-Eilstein N.; Reille-Seroussi M.; Huguenot F.; Vidal M.; Liu W.-Q. Receptors and Clinical Investigation 2015, 2(1), 534.

« Visible light C–H amidation of heteroarenes with benzoyl azides » Brachet, E.; Ghosh, T.; Ghosh, I.; König, B.  Chem. Sci. 2015, 6, 987-992.

« Palladium-Catalyzed Regioselective Alkynylation of Pyrroles and Azoles under Mild Conditions: Application to the Synthesis of a Dopamine D-4 Receptor Agonist » Brachet, E.; Belmont, P.  Org. Chem. 2015, 80, 7519-7529.

« Palladium-Catalyzed Coupling of N-Aminoazoles with 3-Haloquinolin-2(1H)-ones, -Coumarins, -Quinoxalin-2(1H)-ones and -Chromenes, » Luong, T. T. H.; Brachet, E. ; Brion, J.-B. ; Messaoudi, S., Alami, M.  Eur. J. Org. Chem. 2015, 8, 1771-1781.

« Vascular Endothelial Growth Factor Peptide Ligands Explored by Competition Assay and Isothermal Titration Calorimetry. » Reille-Seroussi, M.; Gaucher, J.-F.; Desole, C.; Gagey-Eilstein, N.; Brachet, F.; Broutin, I.; Vidal, M.; Broussy, S. Biochemistry201554, 5147-5156.

« Solid phase synthesis of constrained 13-membered peptide macrocycles employing Fukuyama-Mitsunobu alkylations. » Wang, L.; Liu, W.-Q.; Saraux, N.; Vidal, M.; Broussy, S. Tetrahedron Lett201556, 2456-2459.


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